Plekken in Milan

Giorgio Armani's own fashion museum in a 1950s grain silo

The 1947 cocktail temple where the Negroni Sbagliato was born

Italy's first urban winery, with a Porta Romana wine bar

An 1896 enoteca on Via Paolo Sarpi opening hundreds of labels by the glass

Refined all-day bistrot on patrician Via Vincenzo Monti

Rem Koolhaas-designed contemporary-art campus (skip Bar Luce)

Vintage-apothecary cocktail room on the Naviglio Grande

Italy's largest science museum in a 16th-century monastery

Southern-Italian pastry and proper espresso between Repubblica and Porta Venezia

Milan's great art gallery in the Palazzo di Brera

Eritrean and Ethiopian cooking with a traditional coffee ceremony

Farm-to-table in a restored 17th-century cascina

Brera's artists' bar since 1911

The Pinacoteca di Brera's own bistrot-café